Assessment of detection of Gardnerella vaginalis, Atopobium vaginae, Mobiluncus sp. by real-time PCR in diagnosis of bacterial imbalance in vagina.

 Bacterial vaginosis is a disease. Its importance has been increasing during last years. In Gynaecologic practice it is found in women in 15 to 19%, in pregnant women in 10 to 30% and in women with STI from 30 to 70%. Each second woman does not present any symptoms. This makes difficult to estimate frequency of cases.

Bacterial vaginosis is one of the main factors causing development of pelvic inflammatory diseases and increases risk for pregnancy complications.

More then 50% of cases have unclear clinical presentation or no complications and clinical manifestations. Besides, there is a serious problem in effectiveness of treatment – the disease comes back in 57% of women in 6 months after treatment. This makes timely diagnosis and doctor’s supervision of bacterial vaginosis of crucial importance.

Bacterial vaginosis starts when normal vaginal bacteria have low concentration. This allows conditionally pathogenic bacteria to develop.

Today diagnosis of bacterial vaginosis is based on the results of vaginal swab microscopy and clinical presentation.